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Computational systems biology is the algorithm and application development arm of systems biology. It is also directly associated with bioinformatics and computational biology. Computational systems biology aims to develop and use efficient algorithms, data structures and communication tools to orchestrate the integration of large quantities of biological data with the goal of modelling, and others.
It is understood that an unexpected emergent property of a complex system is a result of the interplay of the cause-and-effect among simpler, integrated parts. Biological systems manifest many important examples of emergent properties in the complex interplay of components. Traditional study of biological systems requires reductive methods in which quantities of data are gathered by category, such as concentration over time in response to a certain stimulus. Computers are critical to analysis and modeling of these data. The goal is to create accurate real-time models of a system's response to environmental and internal stimuli, such as a model of a cancer cell in order to find weaknesses in its signaling pathways, or modeling of ion channel mutations to see effects on cardiomyocytes and in turn, the function of a beating heart.